The Voice of the Genome

Interview Your
Bacterial Genome

Upload your assembled genome and start a conversation. Real bioinformatics analysis. Real science. No external dependencies.

Powered by independent k-mer profiling, sequence-based AMR/virulence detection, MLST typing, and plasmid replicon identification — all running in your browser.

View Methodology

Comprehensive Characterization

Real bioinformatics, not simulations. Every result is traceable to validated methods.

Organism ID

K-mer compositional profiling + GC/size matching. 8 ESKAPE+ Tier 1 priority pathogens.

Assembly Quality

N50/L50/N90, GC analysis, ORF prediction, quality scoring per QUAST standards.

AMR Detection

24+ resistance gene markers. Beta-lactamases, MRSA, VRE, carbapenemases, colistin resistance.

Virulence Factors

30+ virulence markers. Toxins, adhesins, invasion factors, immune evasion, biofilm genes.

MLST Typing

7 MLST schemes with 40+ known STs. Epidemiological context for each clone.

Plasmid Replicons

15+ replicon types. Conjugation assessment, transfer risk, associated resistance.

Scientific Methodology

GenoVox uses the same principles as established bioinformatics tools

Organism Identification

Method: Compositional analysis: GC content + genome size + tetranucleotide frequency signatures + diagnostic markers

References: Karlin & Burge (1995) Trends Genet; Ondov et al. (2016) Genome Biol — same principles as Mash/Kraken2

AMR Gene Detection

Method: Conserved diagnostic marker subsequence search on forward and reverse complement strands

References: Alcock et al. (2023) CARD; Bortolaia et al. (2020) ResFinder; Feldgarden et al. (2019) AMRFinderPlus

Virulence Factor Detection

Method: Curated VF marker sequence matching with category-based pathogenicity scoring

References: Liu et al. (2022) VFDB; Joensen et al. (2014) VirulenceFinder

MLST Typing

Method: Conserved primer-region marker detection for MLST loci + allelic profile matching

References: Jolley et al. (2018) PubMLST; Seemann T — mlst tool

Plasmid Detection

Method: Replicon marker sequence identification on assembled contigs

References: Carattoli et al. (2014) PlasmidFinder; Robertson & Nash (2018) MOB-suite

Scientific Disclaimer

GenoVox provides computational predictions based on genomic markers. Results are for research purposes. Phenotypic antimicrobial susceptibility testing (AST) is essential for clinical decision-making. Genotype does not always predict phenotype.

Tier 1 Priority Pathogens

WHO priority + ESKAPE pathogens — covering ~80% of hospital-acquired infections

E. coli

Escherichia coli

UTI, sepsis, ESBL

K. pneumoniae

Klebsiella pneumoniae

CRE, hvKp

S. aureus

Staphylococcus aureus

MRSA

P. aeruginosa

Pseudomonas aeruginosa

MDR, CF

A. baumannii

Acinetobacter baumannii

XDR, ICU

E. faecium

Enterococcus faecium

VRE

S. enterica

Salmonella enterica

Typhoid, iNTS

M. tuberculosis

Mycobacterium tuberculosis

MDR-TB, XDR-TB

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